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Effects of Long-Term Treatment With ACE Inhibitors in the Presence or Absence of Aspirin; Long-Term Risks Associated with Atrial Fibrillation: 20-Year Follow-up of the Renfrew/Paisley Study; Olfactory
Impairment in Older Adults
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The FDA has recently approved adefovir dipivoxil for the treatment of chronic hepatitis B in adults. This prodrug of adefovir is a nucleotide analog that was originally developed for the treatment of HIV infections but has also been found to be active against the hepatitis B virus.
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There were widespread beneficial effects of high amounts of exercise on plasma lipoproteins.
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Helicobacter pylori is an exceedingly common inhabitant of the human stomach. The discovery of its role in the pathogenesis of peptic ulcer disease was revolutionary, but many questions remain about this organism and an appropriate medical approach to its presence.
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Sodium valproate appears safe and effective for the management of DPSN.
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Synopsis: The Nurses Health Study reports an increased incidence of breast cancer with daily alcohol consumption, hormone therapy, and an additive effect with greater drinking.
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Synopsis: Involvement of a gynecologic oncologist at the time of primary surgery for endometrial cancer was associated with comparable outcomes in both the university and community hospital setting.
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Synopsis: The hazard ratio for death from breast cancer for patients with high total cyclin E levels as compared with those with low total cyclin E levels was 13.3 to about 8 times as high as the hazard ratios associated with other independent clinical and pathological risk factors, including axillary node status.
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Synopsis: Of 217 consecutive Hodgkins disease patients seen at M.D. Anderson with Stage I or II disease who received chemo- and radiation therapy, 12 had elevated b2M (> 2.5 mg/L). There was a trend for reduced relapse-free survival for those with elevated levels, and a significant correlation with reduced overall survival. Thus, an inexpensive and widely available laboratory measure might provide useful prognostic information in patients with Hodgkins disease.